Nicholas Culpeper considered lemon balm to be ruled by Jupiter in Cancer, and suggested it to be used for weak stomachs, to cause the heart to become merry, to help digestion, to open obstructions of the brain, and to expel melancholy vapors from the heart and arteries.
The herbalist John Gerard considered it especially good for feeding and attracting honeybees. The alchemist Paracelsus believed that lemon balm had the power to restore health and vitality. Traditionally, an alchemical tincture of lemon balm was the first tincture an aspiring alchemist made.
Modern herbalists often use lemon balm tea for anxiety, de-stressing, and sleeplessness.